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The most frequently reported cases were in the central nervous system (Migraine, Speech disorders) and gastrointestinal system (Gastrointestinal bleeding, Hepatitis, Stomatitis, Liver failure). Use Acyclovir with great caution in patients taking monoamine oxidase inhibitors . Do not take this medicine without first talking to your doctor if you are pregnant. We therefore tested the hypothesis that Acyclovir inhibits thermoregulatory control. In fact, we are observing some patients who continue to take Acyclovir in order \"to achieve a feeling of well-being,\" even though their pain is controlled after disease regression or switching to strong opioids. 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Acyclovir may impair the mental and or physical Acyclovir buy codabilities required for the performance of potentially hazardous tasks such as driving a car or operating machinery . Gastrointestinal side effects (nausea, dysphagia, vomiting) were reported more frequently with Acyclovir 100 mg, ASA/ codeine, and codeine 60 mg than with placebo. Yates et al. In general, both enantiomers of Acyclovir and M1 follow a parallel time course in the body following single and multiple doses although small differences (~10%) exist in the absolute amount of each enantiomer present. The incidence of nausea and vomiting was significantly higher in the Acyclovir-treated (84%) than in the acetaminophen/codeine treated group (31%). Do not take a larger dose take it more often, or for a longer period than your doctor tells you to. 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Acyclovir is not approved by the FDA for use by children younger than 16 years of age . Acyclovir and its metabolites are excreted primarily in the urine with observed plasma half-lives of 6 . In subjects over 75 years, maximum serum concentrations are elevated (208 vs. Average daily doses of approximately 250 mg of Acyclovir in divided doses were generally comparable to five doses of acetaminophen 300 mg with codeine phosphate 30 mg (TYLENOL® with Codeine #3) daily, five doses of aspirin 325 mg with codeine phosphate 30 mg daily, or two to three doses of acetaminophen 500 mg with oxycodone hydrochloride 5 mg (TYLOX®) daily. It works in certain areas of the brain and nervous system to decrease pain. Serious potential consequences of overdosage with Acyclovir are central nervous system depression, respiratory depression and death . 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